Cataract | Ophthalmology Innovation Source

Icon Bioscience

The company’s proprietary Verisome drug delivery technology is being used as the base for IBI-10090, for post-cataract surgery inflammation. The dexamethasone compound completed a pivotal phase 3 study (n=394), and based on these results, Icon plans to file an NDA by late 2015/early 2016. Phase 3 results builds on the phase 2b data, which showed…

Glaukos

The $4.9 billion glaucoma market is expected to reach $6.6 billion by 2019. The company launched its first product, the iStent, about 2 years ago and has had reasonable market penetration. Further, the company has had tremendous success with getting reimbursement for the device. Prior to the introduction of micro-incisional glaucoma surgery (MIGS), surgery was…

Spotlight on MIGS – Market Overview

Participant: Eric Donnenfeld, MD Eric Donnenfeld, MD is a founding partner of Ophthalmic Consultants of Long Island, Professor of Ophthalmology NYU and a Trustee at Dartmouth Medical School. View Full Profile

Avedro

An ophthalmic panel voted to approve Avedro’s collagen crosslinking device for keratoconus and ectasia, but the FDA did not approve the device. The Complete Response Letter involved only the device, and not the clinical aspects of the trial, and Avedro executives remain confident these last hurdles will be easily overcome. The company is also working…

Sharklet Technologies

Sharklet Technologies has incorporated technology derived from the shark’s ability to remain bacteria-free into a patterned protective membrane. To date, there is “strong in vivo results” showing the lens can facilitate the growth of human lens epithelial cells outside the visual axis, thus eliminating PCO. In lab analyses, when there is a smooth surface, cells…

Clearsight Innovations

Historically, IOL power formulations are good for average refractive outcomes, but poor for predicting an individual’s refractive outcome. The Mirricon may overcome those issues. The ocular biometer for high-performance IOL power calculations provides “results at the push of a button assuring convenience and easy decisions without great expertise and experience,” Mrochen said. An ongoing proof…

PowerVision

PowerVision’s FluidVision is a shape-changing accommodating IOL that has been implanted in more than 100 patients to date. As patients focus on near objects, one drop of the lens’ fluid moves from the periphery to the center of the lens, changing its shape. When the patient focuses on a distance object, the reverse occurs. PowerVision…

Emmetrope

Emmetrope is developing 3 versions of an accommodating lens: single optic ActaLens, dual optic ActaLens-Duo, and shape-changing optic ActaLens-SC, “the future of accommodative lens technology,” said Phillips. To date, small numbers have been enrolled (n=8), but data looks promising—the monofocal hinged silicone ActaLens is injected into the capsular bag through a small corneal incision and…

Mynosys

Zepto is an “innovative, disposable device for cataract surgery,” that uses precision-pulse technology to produce an “accurate and reproducible capsulotomy that is quick, safe, and very affordable,” Hendrick said. The Zepto is comprised of silicone, with a soft, clear suction cup—because of the material choice, surgeons have visibility through the cup. It also includes a…

AcuFocus

Nick Tarantino, Chief Global Clinical Research & Regulatory Affairs Officer AcuFocus’ newest technology, the IC-8 small aperture IOL, builds on the company’s long-term experience with small aperture optics (it developed the KAMRA lens for presbyopia about 10 years ago). The IC-8 essentially takes the KAMRA inlay from the corneal plane to the lens plane. The…

Holland Delivers Overview Of ASCRS, Ophthalmology

[creativ_pullleft colour=”light-gray” colour_custom=”” text=”Episode 031″] ASCRS Program Chair Ed Holland Talks ASCRS Meeting, Technology and Ophthalmology: The Next Generation. Podcast Guest Edward Holland, MD Dr. Holland is the Director of Cornea Services at Cincinnati Eye Institute and Professor of Clinical Ophthalmology at the University of Cincinnati. He has been awarded the Castroviejo Award from the…

Vance Thompson, MD Speaks To Importance Of Patient “Experience” In A Successful Practice

[creativ_pullleft colour=”light-gray” colour_custom=”” text=”Episode 024″] Vance Thompson, MD sees patient “Experience” as a secret weapon in building a successful practice. He shares the steps his group takes to ensure patient service is as big a draw as new technologies. Podcast Guest Vance Thompson, MD Vance Thompson, MD is an internationally recognized specialist in Laser Vision…